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Blood transfusion is the process of transferring blood (or blood-based products) from one person into the circulatory system of another. 

Red blood cells are given to people who don’t have enough red cells of their own to carry oxygen from their lungs to where it is needed in the brain and tissues.

Some people will only need one blood transfusion in their lifetime.  Others, who have blood disorders such as severe anaemia, are dependant on it.  They will have many transfusions in their lifetime. 

The National Blood Service issues about 2 million red cell units a year to people in England and North Wales, mostly for people with cancer and blood disorders.

Blood is a vital resource, but there is not an endless supply of it.   So it’s important that blood components are used efficiently and only where needed.  We need to research transfusion medicine, to identify people who benefit from blood transfusion and people who could be safely treated without the need for transfusion.

At the MRC Clinical Trials Unit, we have collaborated with the National Blood Service since 2001.  We have carried out a study of transfusion recipients to find out the reasons for transfusion and have designed clinical trials to answer the most important questions about the best use of blood.



Medical Research Council Clinical Trials Unit.

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