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The ARROW trial will take place at 3 sites in Uganda and 1 site in Zimbabwe: Data Management, project management and analysis will take place at: A profile of each institution is shown below:

Joint Clinical Research Centre, Uganda

The Joint Clinical Research Centre (JCRC) was founded in 1991 to serve as a national AIDS research centre, and was born as a collaboration between Makerere University's School of Medicine and Uganda's Ministries of Health and Defence. The Centre pioneered the use of anti-HIV drugs in Uganda in 1996, and has since provided anti-HIV drugs to more than 30,000 people.

Joint Clinical Research Centre (JCRC)

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University of Zimbabwe, Harare, Zimbabwe

The University of Zimbabwe is the first and largest university in Zimbabwe. It was founded through a special relationship with the University of London in 1952. The College of Health Sciences is located at Parirenyatwa Hospital. The ARROW clinic is located adjacent to the main hospital.

University of Zimbabwe

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MRC/Uganda Virus Research Institute Programme on AIDS, Entebbe, Uganda

The MRC/UVRI Research Unit on AIDS in Uganda is based at the Uganda Virus Research Institute (UVRI) on the shores of Lake Victoria in Entebbe. Established in 1988 the primary focus of the Programme is to investigate HIV infection issues of public health relevance to Uganda and other parts of sub-Saharan Africa.

MRC/UVRI Research Unit

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The Paediatric Infectious Diseases Clinic (PIDC), Kampala, Uganda.

The PIDC is a specialized AIDS clinic established in 1988. In 2005, it became part of the BIPAI children’s centre of excellence network with the formation of the Baylor College of Medicine Children’s Foundation Uganda. It is based at Mulago Hospital, the largest hospital in Uganda and is currently taking care of over 5000 HIV infected children and adolescents.


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MRC Clinical Trials Unit, London, UK.

The Medical Research Council’s Clinical Trials Unit was set up in 1998 to bring together the expertise of two existing MRC trials units – the MRC Cancer Trials Office in Cambridge and the MRC HIV Clinical Trials Centre – and to develop trials in areas where there was no track record of high quality clinical trials. In 2002, the Co-ordinating Centre for the MRC General Practice Research Framework joined the CTU. By bringing together groups working in a variety of disease areas, they share knowledge and experience of different approaches to trial design, conduct and analysis.

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